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KMID : 1100120150220020083
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대한골대사학회지
2015 Volume.22 No. 2 p.83 ~ p.86
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A First Case of Osteomesopyknosis in Korea
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Jeoung Bi-Na
Kim Jong-Min
Kang Gyoun-Eun
Lim Jang-Hwan
Kim Eui-Hyun
Seo Hyun-Ae
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Abstract
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Osteomesopyknosis is a rare sclerosing bone disorder of autosomal dominant inheritance. We report a first case of osteomesopyknosis in Korea. A 16-year old girl complained of diffuse back pain for 1 year. We performed physical examination, biochemical investigations and imaging studies. A radiograph of spine revealed rugger-jersey vertebra and sandwich vertebra. Bone specific alkaline phosphatase, osteocalcin and C-terminal telopeptides of type I collagen were normal. Only an axial skeleton involvement was shown on the whole body bone scan. This patient was diagnosed to have osteomesopyknosis. Osteomesopyknosis is characterized by normal level of bone turnover marker and an axial bone involvement. Osteomesopyknosis can be occurred in Korea and needs to be considered when patients, especially young patients, suffer from back pain and have only axial osteosclerosis.
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KEYWORD
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Axial osteosclerosis, Bone disease, Back pain
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